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Madecassic acid suppresses osteoclast differentiation and bone resorption by inhibiting RANKL‐induced NF‐κB, JNK and NFAT signaling pathways

Abstract Background Overproduction and activation of osteoclasts result in various bone diseases, such as osteoporosis, Paget's disease, and rheumatoid arthritis. Thus, inhibiting osteoclast formation and overactivation may effectively prevent osteoclast‐related bone diseases, especially osteoporosi...

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Principais autores: Peiru Su, Xiangya Luo, Chunping Zeng, Lin Zhou
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2023-12-01
Serier:Rheumatology & Autoimmunity
Fag:
madecassic acid
nuclear factor‐κB
osteoclastogenesis
osteoclasts
RANKL
Online adgang:https://doi.org/10.1002/rai2.12088
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