Comparative evaluation of heterologous production systems for recombinant pulmonary surfactant protein D

Commercial surfactant products derived from animal lungs are used for the treatment of respiratory diseases in premature neonates. These products contain lipids and the hydrophobic surfactant proteins B and C, which help to lower the surface tension in the lungs. Surfactant products are less effecti...

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Autors principals:	Daniela eSalgado, Rainer eFischer, Stefan eSchillberg, Richard M Twyman, Stefan eRasche
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2014-12-01
Col·lecció:	Frontiers in Immunology
Matèries:	biopharmaceuticals pulmonary surfactant Respiratory Distress Syndrome recombinant protein yield recombinant surfactant protein D heterologous production platform
Accés en línia:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00623/full
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