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Posthemorrhagic hydrocephalus associates with elevated inflammation and CSF hypersecretion via activation of choroidal transporters

Abstract Introduction Posthemorrhagic hydrocephalus (PHH) often develops following hemorrhagic events such as intraventricular hemorrhage (IVH) and subarachnoid hemorrhage (SAH). Treatment is limited to surgical diversion of the cerebrospinal fluid (CSF) since no efficient pharmacological therapies...

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Main Authors: Sara Diana Lolansen, Nina Rostgaard, Dagne Barbuskaite, Tenna Capion, Markus Harboe Olsen, Nicolas H. Norager, Frederik Vilhardt, Søren Norge Andreassen, Trine L. Toft-Bertelsen, Fenghui Ye, Marianne Juhler, Richard F. Keep, Nanna MacAulay
Format: Artigo
Language:Inglês
Published: BMC 2022-08-01
Series:Fluids and Barriers of the CNS
Subjects:
Intraventricular hemorrhage
Subarachnoid hemorrhage
Posthemorrhagic hydrocephalus
Cerebrospinal fluid
Immune response
Biomarkers
Online Access:https://doi.org/10.1186/s12987-022-00360-w
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