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Radiation-Induced Overexpression of TGFβ and PODXL Contributes to Colorectal Cancer Cell Radioresistance through Enhanced Motility

The primary cause of colorectal cancer (CRC) recurrence is increased distant metastasis after radiotherapy, so there is a need for targeted therapeutic approaches to reduce the metastatic-relapse risk. Dysregulation of the cell-surface glycoprotein podocalyxin-like protein (PODXL) plays an important...

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Autori principali: Hyunjung Lee, Joon-Seog Kong, Seung-Sook Lee, Areumnuri Kim
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-08-01
Serie:Cells
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Accesso online:https://www.mdpi.com/2073-4409/10/8/2087
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