Cleavage of the APE1 N-Terminal Domain in Acute Myeloid Leukemia Cells Is Associated with Proteasomal Activity

Apurinic/apyrimidinic endonuclease 1 (APE1), the main mammalian AP-endonuclease for the resolution of DNA damages through the base excision repair (BER) pathway, acts as a multifunctional protein in different key cellular processes. The signals to ensure temporo-spatial regulation of APE1 towards a...

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Principais autores:	Lisa Lirussi, Giulia Antoniali, Pasqualina Liana Scognamiglio, Daniela Marasco, Emiliano Dalla, Chiara D’Ambrosio, Simona Arena, Andrea Scaloni, Gianluca Tell
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2020-03-01
Series:	Biomolecules
Assuntos:	apurinic apyrimidinic endonuclease/redox effector factor 1 cytoplasmic nucleophosmin 1 proteasome acute myeloid leukemia proteolysis
Acceso en liña:	https://www.mdpi.com/2218-273X/10/4/531
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