Mechanism-informed neuroprotection in acute ischemic stroke treated with thrombectomy: a systematic review and meta-analysis of randomized controlled trials

BackgroundDespite the success of endovascular thrombectomy (EVT) in restoring large-vessel patency in acute ischemic stroke (AIS), a substantial proportion of patients fail to achieve functional independence, largely due to ischemia-reperfusion injury (IRI) at the tissue level. Pharmacological neuro...

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Auteurs principaux:	Yuchen Wang, Jie Xu, Zhiheng Zhao, Ruizhe Yang, Xin Zhou, Zhang Yang
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-06-01
Collection:	Frontiers in Pharmacology
Sujets:	acute ischemic stroke cerebroprotection endovascular thrombectomy ischemia-reperfusion injury meta-analysis neuroprotective agents
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1843513/full
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