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Development of a Bicistronic Yellow Fever Live Attenuated Vaccine with Reduced Neurovirulence and Viscerotropism

ABSTRACT The yellow fever (YF) live attenuated vaccine strain 17D (termed 17D) has been widely used for the prevention and control of YF disease. However, 17D retains significant neurovirulence and viscerotropism in mice, which is probably linked to the increased occurrences of serious adverse event...

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書誌詳細
主要な著者: Hong-Jiang Wang, Yan Guo, Meng-Jiao He, Zhong-Yu Liu, Qing Ye, Xing-Yao Huang, Yong-Qiang Deng, Xiao-Feng Li, Cheng-Feng Qin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2022-10-01
シリーズ:Microbiology Spectrum
主題:
オンライン・アクセス:https://journals.asm.org/doi/10.1128/spectrum.02246-22
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