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Effects of Radiation-Induced Skin Injury on Hyaluronan Degradation and Its Underlying Mechanisms

Radiation-induced skin injury (RISI) is a frequent and severe complication with a complex pathogenesis that often occurs during radiation therapy, nuclear incidents, and nuclear war, for which there is no effective treatment. Hyaluronan (HA) plays an overwhelming role in the skin, and it has been sh...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Jiahui Dong, Boyuan Ren, Yunfei Tian, Guanqun Peng, Huiting Zhai, Zhiyun Meng, Ruolan Gu, Hui Gan, Zhuona Wu, Yunbo Sun, Guifang Dou, Shuchen Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-11-01
Schriftenreihe:Molecules
Schlagworte:
radiation-induced skin injury
hyaluronan
degradation
mechanisms
<i>MEK5</i>/<i>ERK5</i> pathway
inflammatory factors
Online-Zugang:https://www.mdpi.com/1420-3049/28/21/7449
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