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Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study

Abstract Background Observational studies have linked childhood obesity with elevated risk of colorectal cancer; however, it is unclear if this association is causal or independent from the effects of obesity in adulthood on colorectal cancer risk. Methods We conducted Mendelian randomization (MR) a...

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Principais autores: Nikos Papadimitriou, Caroline J. Bull, Mazda Jenab, David J. Hughes, Joshua A. Bell, Eleanor Sanderson, Nicholas J. Timpson, George Davey Smith, Demetrius Albanes, Peter T. Campbell, Sébastien Küry, Loic Le Marchand, Cornelia M. Ulrich, Kala Visvanathan, Jane C. Figueiredo, Polly A. Newcomb, Rish K. Pai, Ulrike Peters, Kostas K. Tsilidis, Jolanda M. A. Boer, Emma E. Vincent, Daniela Mariosa, Marc J. Gunter, Tom G. Richardson, Neil Murphy
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2023-01-01
סדרה:BMC Medicine
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גישה מקוונת:https://doi.org/10.1186/s12916-022-02702-9
תגים: הוספת תג
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