Interferon-α stimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis

Abstract Background Liver ischemia/reperfusion (I/R) injury is usually caused by hepatic inflow occlusion during liver surgery, and is frequently observed during war wounds and trauma. Hepatocyte ferroptosis plays a critical role in liver I/R injury, however, it remains unclear whether this process...

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Principais autores:	Kai-Wei Jia, Ren-Qi Yao, Yi-Wen Fan, Ding-Ji Zhang, Ye Zhou, Min-Jun Wang, Li-Yuan Zhang, Yue Dong, Zhi-Xuan Li, Su-Yuan Wang, Mu Wang, Yun-Hui Li, Lu-Xin Zhang, Ting Lei, Liang-Chen Gui, Shan Lu, Ying-Yun Yang, Si-Xian Wang, Yi-Zhi Yu, Yong-Ming Yao, Jin Hou
Format:	Artigo
Jezik:	Inglês
Izdano:	KeAi Communications Co., Ltd. 2024-04-01
Serija:	Military Medical Research
Teme:	Ischemia/reperfusion (I/R) DExH-box helicase 58 (DHX58) Glutathione peroxidase 4 (GPX4) m6A modification YT521-B homology domain containing 2 (YTHDC2)
Online dostop:	https://doi.org/10.1186/s40779-024-00524-9
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