Co-assembling de novo designed peptide with high-payload drug protein for noninvasive treatment of corneal neovascularization

The specificity and low toxicity of protein drugs are significant for disease treatment but are strongly limited by their weak tissue penetrative capacity. Although formulating proteins with nanoparticle is an alternative strategy, the low encapsulation efficiency (EE) and loading capacity (LC) of p...

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Bibliografische Detailangaben

Hauptverfasser:	Yuhua Tong, Sijie Zhou, Yongjie Guo, Xiaoli Jin, Meiting Yu, Chunyun Feng, Hao Chen, Xingjie Zan, Jinyang Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-12-01
Schriftenreihe:	International Journal of Pharmaceutics: X
Schlagworte:	Protein delivery Peptide assembly Protein drug Corneal neovascularization Nanomedicine
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2590156725000957
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