Generation of a TSC2 knockout embryonic stem cell line by CRISPR/Cas9 editing
Tuberous Sclerosis Complex (TSC) is a severe developmental disorder with various clinical effects, primarily caused by TSC2 gene mutations, often involving loss of function(Henske,et al., 2016).To explore role of TSC2 in human heart development, we successfully developed a TSC2 knockout (TSC2-/-) hu...
Kaydedildi:
| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2024-06-01
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| Seri Bilgileri: | Stem Cell Research |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S1873506124000977 |
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