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Breast carcinomas associated with microglandular adenosis are linked to germline alterations in homologous recombination-deficiency genes

Abstract Invasive breast carcinomas associated with microglandular adenosis (IBC-MGA) represent a rare and poorly characterized form of triple-negative breast cancer (TNBC). We analyzed clinical, pathological, and germline genetic data from 38 patients, including 34 IBC-MGAs and 4 in situ cases. Ger...

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Autors principals: Christopher J. Schwartz, Iskender Genco, Matteo Repetto, Daniel Muldoon, Andrea Gazzo, Panieh Terraf, Anne Grabenstetter, Dara Ross, Hong Zhang, Diana Mandelker, Simon Powell, Britta Weigelt, Chaitanya Bandlamudi, Edi Brogi, Fresia Pareja, Hannah Y. Wen
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-07-01
Col·lecció:npj Breast Cancer
Accés en línia:https://doi.org/10.1038/s41523-025-00794-z
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