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Mechanistic study of cancer-associated fibroblast senescence and cervical cancer cell invasiveness and radio-resistance conferred by IL-6 through activation of STAT3 and Notch signaling

Background and purpose: Senescent cancer-associated fibroblasts (CAFs) in tumor microenvironment are known to mediate the invasion and radio- or chemo-resistance of epithelial cancers. The inflammatory cytokine IL-6 derived from CAFs may promote the invasion and radio-resistance of epithelial cervic...

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Bibliografiske detaljer
Principais autores: 任春霞, 马锦琪, 吕祝武
Format: Artigo
Sprog:Inglês
Udgivet: Editorial Office of China Oncology 2016-01-01
Serier:Zhongguo aizheng zazhi
Fag:
Online adgang:http://www.china-oncology.com/thesisDetails#10.19401/j.cnki.1007-3639.2016.12.001
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