Identification of miR-20b-5p as an inhibitory regulator in cardiac differentiation via TET2 and DNA hydroxymethylation

Abstract Background Congenital heart disease (CHD) is a prevalent congenital cardiac malformation, which lacks effective early biological diagnosis and intervention. MicroRNAs, as epigenetic regulators of cardiac development, provide potential biomarkers for the diagnosis and treatment of CHD. Howev...

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Detalhes bibliográficos

Principais autores:	Ke-Xin Li, Jia-Ru Li, Sheng-Jia Zuo, Xudong Li, Xian-Tong Chen, Pei-Yi Xiao, Hui-Tao Li, Ling Sun, Tao Qian, Hao-Min Zhang, Dongxing Zhu, Xi-Yong Yu, Guojun Chen, Xue-Yan Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-03-01
coleção:	Clinical Epigenetics
Assuntos:	MicroRNA-20b-5p Cardiac differentiation Tet methylcytosine dioxygenase 2 (TET2) DNA hydroxymethylation
Acesso em linha:	https://doi.org/10.1186/s13148-024-01653-7
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