Plasmid-free production of the plant lignan pinoresinol in growing Escherichia coli cells

Abstract Background The high-value aryl tetralin lignan (+)-pinoresinol is the main precursor of many plant lignans including (-)-podophyllotoxin, which is used for the synthesis of chemotherapeutics. As (-)-podophyllotoxin is traditionally isolated from endangered and therefore limited natural sour...

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Autores principales:	U. Joost Luelf, Alexander Wassing, Lisa M. Böhmer, Vlada B. Urlacher
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-10-01
Colección:	Microbial Cell Factories
Materias:	Phenylpropanoid Coniferyl alcohol Ferulic acid Lignan Pinoresinol Oxidative coupling
Acceso en línea:	https://doi.org/10.1186/s12934-024-02562-3
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