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Systematic Review of Safety and Efficacy of Second- and Third-Generation CD20-Targeting Biologics in Treating Immune-Mediated Disorders

BackgroundB cells can contribute to immune-mediated disorders. Targeting CD20 has proved to be efficacious in several B cell-mediated immunopathologies, as illustrated by the use of rituximab, the first anti-CD20 monoclonal antibody (mAb). Following rituximab, second- and third-generation anti-CD20...

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Hlavní autoři: Celine Kaegi, Benjamin Wuest, Catherine Crowley, Onur Boyman
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-02-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2021.788830/full
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