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Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse [version 2; referees: 2 approved]

Background: Mutations of the common cytokine receptor gamma chain (γc) cause Severe Combined Immunodeficiency characterized by absent T and NK cell development. Although stem cell therapy restores these lineages, residual immune defects are observed that may result from selective persistence of γc-d...

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Principais autores: Chiara Beilin, Kaushik Choudhuri, Gerben Bouma, Dessislava Malinova, Jaime Llodra, David L. Stokes, Motumu Shimaoka, Timothy A. Springer, Michael L. Dustin, Adrian J. Thrasher, Siobhan O. Burns
Formato: Artigo
Idioma:Inglês
Publicado: Wellcome 2018-10-01
Series:Wellcome Open Research
Acceso en liña:https://wellcomeopenresearch.org/articles/3-84/v2
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