Inhibition of gasdermin D attenuates neutrophil extracellular trap formation induced by platelet-derived exosome in necrotizing enterocolitis

Abstract Necrotizing enterocolitis (NEC) is a critical gastrointestinal disorder observed in neonates, defined by intestinal inflammation and tissue necrosis. This research examines the involvement of gasdermin D (GSDMD) in platelet pyroptosis and its effect on the formation of neutrophil extracellu...

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Detalhes bibliográficos

Principais autores:	Yunfei Zhang, Kai Gao, Cuilian Ye, Qin Deng, Xinzhong, Yue Ma, Chunbao Guo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
coleção:	Cell Communication and Signaling
Assuntos:	Necrotizing enterocolitis Gasdermin D Neutrophil Extracellular Trap Platelet Exosome
Acesso em linha:	https://doi.org/10.1186/s12964-026-02888-y
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