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Targeted Drug Delivery Technologies Potentiate the Overall Therapeutic Efficacy of an Indole Derivative in a Mouse Cystic Fibrosis Setting

Inflammation plays a major role in the pathophysiology of cystic fibrosis (CF), a multisystem disease. Anti-inflammatory therapies are, therefore, of interest in CF, provided that the inhibition of inflammation does not compromise the ability to fight pathogens. Here, we assess whether indole-3-alde...

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Main Authors: Matteo Puccetti, Marilena Pariano, Giorgia Renga, Ilaria Santarelli, Fiorella D’Onofrio, Marina M. Bellet, Claudia Stincardini, Andrea Bartoli, Claudio Costantini, Luigina Romani, Maurizio Ricci, Stefano Giovagnoli
Format: Artigo
Language:Inglês
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
cystic fibrosis
inflammation
aryl hydrocarbon receptor
drug delivery
3-IAld
Online Access:https://www.mdpi.com/2073-4409/10/7/1601
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