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Investigating the mechanism of Gentiopicroside in rheumatoid arthritis through network pharmacology, molecular docking, and experimental validation

Abstract Rheumatoid arthritis (RA) constitutes a chronic, progressive autoimmune disease, and effective treatment of RA remains a challenge. Due to the multiple side effects and “therapeutic ceiling” effect of current RA medications, it is essential to find natural alternatives and explore their mec...

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Autors principals: Rongyue Jing, Yueyue Chen, Meimei Xu, Xudan Zou, Suling Wu
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2025-06-01
Col·lecció:Scientific Reports
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Accés en línia:https://doi.org/10.1038/s41598-025-03818-7
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