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Chemokine CXCL12 drives pericyte accumulation and airway remodeling in allergic airway disease

Abstract Background Airway remodeling is a significant contributor to impaired lung function in chronic allergic airway disease. Currently, no therapy exists that is capable of targeting these structural changes and the consequent loss of function. In the context of chronic allergic inflammation, pe...

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Principais autores: Rebecca Bignold, Bushra Shammout, Jessica E. Rowley, Mariaelena Repici, John Simms, Jill R. Johnson
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2022-07-01
Series:Respiratory Research
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Acceso en liña:https://doi.org/10.1186/s12931-022-02108-4
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