Alendronic acid modified PLGA drug delivery system loaded with 17β-Estradiol and vitamin D3 has anti-osteoporotic effect

Postmenopausal osteoporosis caused by estrogen deficiency often requires hormone replacement therapy (HRT), but its systemic side effects limit clinical application. Here, we developed a bone-targeted Poly (lactic-co-glycolic acid) (PLGA) nanocarrier modified with Alendronic acid (ADA) to co-deliver...

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Bibliografische Detailangaben

Hauptverfasser:	Yonghui Wang, Sidi Zhang, Xinrun Ma, Donghao Hu, Junran Liu, Lu Wei, Xue Lei, Yan Hu, Fuyou Li, Yanhong Gao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-04-01
Schriftenreihe:	Materials Today Bio
Schlagworte:	Alendronic acid 17β-Estradiol Vitamin D3 Osteoporosis
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2590006426000311
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