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The unfolded protein response regulates ER exit sites via SNRPB-dependent RNA splicing and contributes to bone development

Abstract Splicing and endoplasmic reticulum (ER)-proteostasis are two key processes that ultimately regulate the functional proteins that are produced by a cell. However, the extent to which these processes interact remains poorly understood. Here, we identify SNRPB and other components of the Sm-ri...

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Principais autores: Muhammad Zahoor, Yanchen Dong, Marco Preussner, Veronika Reiterer, Sabrina Shameen Alam, Margot Haun, Utku Horzum, Yannick Frey, Renata Hajdu, Stephan Geley, Valerie Cormier-Daire, Florian Heyd, Loydie A Jerome-Majewska, Hesso Farhan
Format: Artigo
Sprog:Inglês
Udgivet: Springer Nature 2024-08-01
Serier:The EMBO Journal
Fag:
COPII
Endoplasmic Reticulum
Sec16A
Proteostasis
Splicing
Online adgang:https://doi.org/10.1038/s44318-024-00208-z
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