Autocrine Effects of Brain Endothelial Cell-Produced Human Apolipoprotein E on Metabolism and Inflammation in vitro

Reports of APOE4-associated neurovascular dysfunction during aging and in neurodegenerative disorders has led to ongoing research to identify underlying mechanisms. In this study, we focused on whether the APOE genotype of brain endothelial cells modulates their own phenotype. We utilized a modified...

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Autores principales:	Felecia M. Marottoli, Troy N. Trevino, Xue Geng, Zarema Arbieva, Pinal Kanabar, Mark Maienschein-Cline, James C. Lee, Sarah E. Lutz, Leon M. Tai
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2021-06-01
Colección:	Frontiers in Cell and Developmental Biology
Materias:	apolipoprotein E brain endothelial cells metabolism inflammation SR9009
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fcell.2021.668296/full
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