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Microbiome-derived bacterial lipids regulate gene expression of proinflammatory pathway inhibitors in systemic monocytes

How the microbiome regulates responses of systemic innate immune cells is unclear. In the present study, our purpose was to document a novel mechanism by which the microbiome mediates crosstalk with the systemic innate immune system. We have identified a family of microbiome Bacteroidota-derived lip...

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Autori principali: Saki Mihori, Frank Nichols, Anthony Provatas, Alyssa Matz, Beiyan Zhou, Christopher N. Blesso, Hunter Panier, Lauren Daddi, Yanjiao Zhou, Robert B. Clark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-06-01
Serie:Frontiers in Immunology
Soggetti:
microbiome
innate immunity
inhibitors
bacterial lipids
TLR
proinflammatory pathways
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1415565/full
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