Clinical Relevance of Serum Kyn/Trp Ratio and Basal and IFNγ-Upregulated IDO1 Expression in Peripheral Monocytes in Early Stage Melanoma

Immune escape is an early phenomenon in cancer development/progression. Indoleamine 2,3-dioxygenase 1 (IDO1) is a normal endogenous mechanism of acquired peripheral immune tolerance and may therefore be tumor-promoting. This study investigated the clinical relevance of IDO1 expression by immune cell...

Cijeli opis

Bibliografski detalji

Glavni autori:	Annabel Meireson, Liesbeth Ferdinande, Marc Haspeslagh, Benjamin Hennart, Delphine Allorge, Piet Ost, Nora Sundahl, Mathieu Spaas, Annelies Demeyer, Lieve Brochez
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2021-09-01
Serija:	Frontiers in Immunology
Teme:	early stage melanoma biomarker IDO1 Kyn/Trp tryptophan metabolism monocytes
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.736498/full
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!