The effects of social environment on AD-related pathology in hAPP-J20 mice and tau-P301L mice

In humans, social factors (e.g., loneliness) have been linked to the risk of developing Alzheimer's Disease (AD). To date, AD pathology is primarily characterized by amyloid-β plaques and tau tangles. We aimed to assess the effect of single- and group-housing on AD-related pathology in a mouse model...

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Autors principals:	Suzanne D. Lanooij, W.H.I.M. Drinkenburg, U.L.M. Eisel, E.A. van der Zee, Martien J.H. Kas
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-10-01
Col·lecció:	Neurobiology of Disease
Matèries:	Alzheimer's disease Transgenic mice Amyloid pathology Tau pathology Social environment Social isolation
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S096999612300325X
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