Loss of the putative Rab GTPase, Ypt7, impairs the virulence of Cryptococcus neoformans

Small GTPases of the Rab family coordinate multiple membrane fusion and trafficking events in eukaryotes. In fungi, the Rab GTPase, Ypt7, plays a critical role in late endosomal trafficking, and is required for homotypic fusion events in vacuole biogenesis and inheritance. In this study, we identifi...

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Bibliografische Detailangaben

Hauptverfasser:	Guanggan Hu, Xianya Qu, Kabir Bhalla, Peng Xue, Erik Bakkeren, Christopher W. J. Lee, James W. Kronstad
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-07-01
Schriftenreihe:	Frontiers in Microbiology
Schlagworte:	endomembrane trafficking fungal pathogenesis iron heme vacuole cryptococcosis
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmicb.2024.1437579/full
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