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Mechanistic models with experimental comparison for microwave-assisted lyophilization in a vial

Abstract Microwave heating has been shown to accelerate pharmaceutical lyophilization but robust process models, crucial to ensuring that the process is efficient without damaging products, are still scarce. Building on both high-frequency microwave lyophilization experiments and recent modeling eff...

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Autors principals: Isaac S. Wheeler, Ahmad Darwish, Vivek Narsimhan, Alina A. Alexeenko
Format: Artigo
Idioma:Inglês
Publicat: SpringerOpen 2026-07-01
Col·lecció:AAPS Open
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Accés en línia:https://doi.org/10.1186/s41120-026-00173-3
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