Epitope Mapping of Monoclonal Antibodies to Calreticulin Reveals That Charged Amino Acids Are Essential for Antibody Binding

Calreticulin is a chaperone protein, which is associated with myeloproliferative diseases. In this study, we used resin-bound peptides to characterize two monoclonal antibodies (mAbs) directed to calreticulin, mAb FMC 75 and mAb 16, which both have significantly contributed to understanding the biol...

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Hlavní autoři:	Ann Christina Bergmann, Cecilie Kyllesbech, Rimantas Slibinskas, Evaldas Ciplys, Peter Højrup, Nicole Hartwig Trier, Gunnar Houen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-08-01
Edice:	Antibodies
Témata:	antibody calreticulin epitope enzyme-linked immunosorbent assay
On-line přístup:	https://www.mdpi.com/2073-4468/10/3/31
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