Evaluating the immune effector functions induced by humanized anti-CD99 antibody in eliminating T lymphoblastic leukemia/lymphoma cells

Abstract Monoclonal antibodies (mAbs) have emerged as targeted immunotherapies with clinical effectiveness and low adverse effects for various cancers. However, antibody drugs for treating aggressive T cell malignancies, T lymphoblastic leukemia/lymphoma (T-ALL/T-LBL), are still limited. Therefore,...

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Principais autores:	Kamonporn Kotemul, Ratthakorn Chaiwut, Chaochetdhapada Putpim, Supansa Pata, Witida Laopajon, Chatchai Tayapiwatana, Watchara Kasinrerk, Nuchjira Takheaw
Formato:	Artigo
Idioma:	Inglês
Publicado:	Springer 2025-04-01
Series:	Discover Oncology
Assuntos:	Monoclonal antibody CD99 molecule Cancer immunotherapy T lymphoblastic leukemia/lymphoma Anticancer activities Immune effector functions
Acceso en liña:	https://doi.org/10.1007/s12672-025-02281-0
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