Impact of Intrahost NS5 Nucleotide Variations on Dengue Virus Replication
Due to the nature of RNA viruses, their high mutation rates produce a population of closely related but genetically diverse viruses, termed quasispecies. To determine the role of quasispecies in DENV disease severity, 22 isolates (10 from mild cases, 12 from fatal cases) were obtained, amplified, an...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2022-07-01
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| coleção: | Frontiers in Microbiology |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.894200/full |
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