γH2AX and p53 Immunohistochemistry predict the incidence risk of esophageal squamous precancerous lesions

Abstract Background Current screening practices for esophageal squamous cell carcinoma (ESCC) subject to both over- and under-surveillance of precancerous lesions. This study aims to evaluate potential immunohistochemical (IHC) markers associated with the incidence of ESCC and to establish an IHC-ba...

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Главные авторы:	Xiangwen Cheng, Ying Liu, Huanyu Chen, Yaqi Pan, Zhe Hu, Zhen Liu, Fangfang Liu, Wenlei Yang, Chuanhai Guo, Lixin Zhang, Liheng Zhang, Fenglei Li, Jiangang Li, Xinna Liu, Haijun Yang, Muyan Cai, Mengfei Liu, Zhonghu He, Yang Ke
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2026-05-01
Серии:	BMC Medicine
Предметы:	Esophageal squamous cell carcinoma Precancerous lesions Surveillance Immunohistochemical markers Risk stratification
Online-ссылка:	https://doi.org/10.1186/s12916-026-04902-z
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