Identification of engineered IMGT Fc variants in IMGT/mAb-DB, a database of therapeutic antibodies and fusion proteins

Monoclonal antibodies (mAbs) and fusion proteins for immune applications (FPIA) play a crucial role in treating autoimmune diseases and cancers by targeting cell-surface proteins and triggering multiple immune mechanisms. These functions are mediated by the crystallizable fragment (Fc) region of mAb...

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Hlavní autoři:	Taciana Manso, Gaoussou Sanou, Christos Nousias, Imene Maalem, François Boutin, Véronique Giudicelli, Patrice Duroux, Marie-Paule Lefranc, Sofia Kossida
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2025-12-01
Edice:	mAbs
Témata:	Antibody engineering Fc variants IMGT immunotherapy monoclonal antibodies
On-line přístup:	https://www.tandfonline.com/doi/10.1080/19420862.2025.2594260
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