Advances in the Structure of GGGGCC Repeat RNA Sequence and Its Interaction with Small Molecules and Protein Partners

The aberrant expansion of GGGGCC hexanucleotide repeats within the first intron of the <i>C9orf72</i> gene represent the predominant genetic etiology underlying amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). The transcribed r(GGGGCC)_n RNA repeats form RNA foci, w...

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Váldodahkkit:	Xiaole Liu, Xinyue Zhao, Jinhan He, Sishi Wang, Xinfei Shen, Qingfeng Liu, Shenlin Wang
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	MDPI AG 2023-08-01
Ráidu:	Molecules
Fáttát:	amyotrophic lateral sclerosis frontotemporal dementia <i>C9orf72</i> GGGGCC G4
Liŋkkat:	https://www.mdpi.com/1420-3049/28/15/5801
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