Synthesis, spectral analysis and pharmacological study of N'- substituted-2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazides

ABSTRACT A series of molecules bearing multiple functional groups were synthesized to study their antibiotic effect against Gram-positive and Gram-negative bacteria and lipoxygenase activity as well. 2,4-Dimethylcarbolic acid (1) was refluxed with ethyl 2-bromoacetate to synthesize ethyl 2-(2,4-dime...

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Detalhes bibliográficos

Principais autores:	Shahid Rasool, Aziz-ur-Rehman, Muhammad Athar Abbasi, Sabahat Z Siddiqui, Syed Adnan Ali Shah
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
coleção:	Brazilian Journal of Pharmaceutical Sciences
Assuntos:	Acetohydrazides/ Synthesis Acetohydrazides/Antibacterial activity/ Acetohydrazides/Lipoxygenase/inhibition activity.
Acesso em linha:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000300471&lng=en&tlng=en
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