Evaluation of non-motor symptoms in Parkinson’s disease using multiparametric MRI with the multiplex sequence

BackgroundNon-motor symptoms (NMS) in Parkinson’s disease (PD) often precede motor manifestations and are challenging to detect with conventional MRI. This study investigates the use of the Multi-Flip-Angle and Multi-Echo Gradient Echo Sequence (MULTIPLEX) in MRI to detect previously undetectable mi...

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Главные авторы:	He Sui, Zhanhao Mo, Feng Shi, Qing Zhou, Dan Yu, Jiaqi Wang, Lin Liu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2025-07-01
Серии:	Frontiers in Aging Neuroscience
Предметы:	Parkinson’s disease non-motor symptoms quantitative MRI analysis brain segmentation early diagnosis
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fnagi.2025.1602245/full
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