Anti-atherosclerotic effect of lipid/cholesterol-cyclodextrin inclusion complexes similar to free cyclodextrins in ApoE-/- mice fed a high-fat diet

Cyclodextrins have long been used as a drug excipient (e.g., drug-cyclodextrin inclusion complex) to ameliorate the water solubility and taste of drugs. Cyclodextrins are cyclic oligosaccharide molecules featuring a hydrophobic inner cavity and a hydrophilic outer surface. Drugs are physically encap...

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Autori principali:	Yuanfang Li, Yuan Zhang, Mengyi Lan, Zhilu Fan, Tingting Gong, Langtao Xu, Tong Rong, Kun Wang, Huaying Wang, Meiying Ao, Yong Chen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-06-01
Serie:	Carbohydrate Polymer Technologies and Applications
Soggetti:	Atherosclerosis Hydroxypropyl-β-cyclodextrin (HPβCD) Cholesterol Liposomes particle size Serum extraction Inclusion complex
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2666893925001495
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