Extracellular Acidification Induces Lysosomal Dysregulation

Many invasive cancers emerge through a years-long process of somatic evolution, characterized by an accumulation of heritable genetic and epigenetic changes and the emergence of increasingly aggressive clonal populations. In solid tumors, such as breast ductal carcinoma, the extracellular environmen...

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主要な著者:	Bryce Ordway, Robert J. Gillies, Mehdi Damaghi
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2021-05-01
シリーズ:	Cells
主題:	cancer acidosis lysosome dysregulation lysosomal localization tumor microenvironment Warburg effect targeted therapy
オンライン･アクセス:	https://www.mdpi.com/2073-4409/10/5/1188
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