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Allometry correction in semi-quantitative analysis of dopamine transporter SPECT

Abstract Background Striatal specific binding ratios (SBR) are widely used to support the interpretation of dopamine transporter SPECT scans. Automatic SBR computation often involves using affine transformations to map the individual SPECT images to an anatomical reference space for ROI analysis usi...

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Autori principali: Thomas Buddenkotte, Ivayla Apostolova, Susanne Klutmann, Ralph Buchert
Natura: Artigo
Lingua:Inglês
Pubblicazione: SpringerOpen 2025-12-01
Serie:EJNMMI Research
Soggetti:
SPECT
Dopamine transporter
[123I]FP-CIT
Ioflupane
Specific binding ratio
Spatial normalization
Accesso online:https://doi.org/10.1186/s13550-025-01353-0
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