Calcitriol restrains microglial M1 polarization and alleviates dopaminergic degeneration in hemiparkinsonian mice by boosting regulatory T‐cell expansion

Abstract Objective Vitamin D deficiency is a risk factor for Parkinson's disease (PD) and vitamin D supplementation robustly alleviates neurodegeneration in PD models. However, the mechanisms underlying this effect require further clarification. Current evidence suggests that harnessing regulatory T...

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Hauptverfasser:	Yangzhi Xie, Liang Chen, Jiacheng Chen, Yongjun Chen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2024-02-01
Schriftenreihe:	Brain and Behavior
Schlagworte:	M1/M2 polarization neuroinflammation Parkinson's disease regulatory T cell vitamin D receptor
Online-Zugang:	https://doi.org/10.1002/brb3.3373
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