MYSM1 Represses Innate Immunity and Autoimmunity through Suppressing the cGAS-STING Pathway

Summary: The immune system is not only required for preventing threats exerted by pathogens but also essential for developing immune tolerance to avoid tissue damage. This study identifies a distinct mechanism by which MYSM1 suppresses innate immunity and autoimmunity. The expression of MYSM1 is ind...

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Autors principals:	Mingfu Tian, Weiyong Liu, Qi Zhang, Yuqing Huang, Wen Li, Wenbiao Wang, Peiyi Zhao, Shanyu Huang, Yunting Song, Muhammad Adnan Shereen, Mengying Qin, Yingle Liu, Kailang Wu, Jianguo Wu
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2020-10-01
Col·lecció:	Cell Reports
Matèries:	adenovirus ADV autoimmune disease autoimmunity cyclic GMP-AMP synthase cGAS
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211124720312869
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