Hijacking PrPC-dependent signal transduction: when prions impair Αβ clearance
The cellular prion protein PrPC is the normal counterpart of the scrapie prion protein PrPSc, the main component of the infectious agent of Transmissible Spongiform Encephalopathies. The recent discovery that PrPC can serve as a receptor for the amyloid Αβ peptide and relay its neurotoxicity is spar...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Frontiers Media S.A.
2014-02-01
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| श्रृंखला: | Frontiers in Aging Neuroscience |
| विषय: | |
| ऑनलाइन पहुंच: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00025/full |
| टैग: |
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