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Identification of anaphase promoting complex substrates in S. cerevisiae.

The Anaphase-Promoting Complex/Cyclosome (APC/C) is an essential ubiquitin ligase that targets numerous proteins for proteasome-mediated degradation in mitosis and G1. To gain further insight into cellular pathways controlled by APC/C(Cdh1), we developed two complementary approaches to identify addi...

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Principais autores: Denis Ostapenko, Janet L Burton, Mark J Solomon
格式: Artigo
语言:Inglês
出版: Public Library of Science (PLoS) 2012-01-01
丛编:PLoS ONE
在线阅读:http://europepmc.org/articles/PMC3458821?pdf=render
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