A smart multiantenna gene theranostic system based on the programmed assembly of hypoxia-related siRNAs
The therapeutic application of small interfering RNA (siRNA) is challenging due to its non-specific targeting and delivery issues. Here, the authors report an endogenous micro-RNA guided and hybridisation chain reaction-promoted siRNA delivery system encapsulated in tumour-derived extracellular vesi...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Portfolio
2021-06-01
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| Serija: | Nature Communications |
| Online dostop: | https://doi.org/10.1038/s41467-021-24191-9 |
| Oznake: |
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