Genome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring
The emergence of the CRISPR-Cas9 system has triggered a technical revolution in mammalian genome editing. Compared to traditional gene-targeting strategies, CRISPR-Cas9 technology offers a more efficient and cost-effective approach for generating genetically modified animal models. However, off-targ...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2019-11-01
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| Collection: | G3: Genes, Genomes, Genetics |
| Sujets: | |
| Accès en ligne: | http://g3journal.org/lookup/doi/10.1534/g3.119.400503 |
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