Inhibition of Y1 receptor signaling improves islet transplant outcome
Islet transplantation is considered one of the potential treatments for T1DM but limited islet survival and their impaired function pose limitations to this approach. Here Loh et al. show that the Y1 receptor is expressed in β- cells and inhibition of its signalling, both genetic and pharmacological...
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| Principais autores: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2017-09-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-017-00624-2 |
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