TYMP upregulation mediated by the hyperactivated IL-17/NF-κB1 axis promotes psoriasis through enhancing aberrant keratinization and neutrophil-mediated inflammation

Abstract Psoriasis is a common, chronic, and recurrent immune-mediated disorder with global prevalence, underscoring the need for novel biomarkers to improve diagnosis and treatment. In this study, differentially expressed genes (DEGs) in psoriatic tissues were comprehensively identified through int...

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Bibliografiska uppgifter

Huvudupphov:	Jing Wang, Zeng Zhou, Yanyan Chen, Qiang Li, Lantian Zhai, Dandan Li, Shanshan Qin, Yanling He
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2026-04-01
Serie:	Biology Direct
Ämnen:	Biomarker Keratinization Neutrophil degranulation Psoriasis IL-17 signaling pathway
Länkar:	https://doi.org/10.1186/s13062-026-00734-2
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