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Caenorhabditis elegans MES-3 is a highly divergent ortholog of the canonical PRC2 component SUZ12

Summary: Polycomb Repressive Complex 2 (PRC2) catalyzes the mono-, di-, and trimethylation of histone protein H3 on lysine 27 (H3K27), which is strongly associated with transcriptionally silent chromatin. The functional core of PRC2 is highly conserved in animals and consists of four subunits. One o...

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Bibliografische Detailangaben
Hauptverfasser: Berend Snel, Sander van den Heuvel, Michael F. Seidl
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2022-07-01
Schriftenreihe:iScience
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2589004222009051
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